Our Team
Principal Investigator
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Akiko Shimamura, MD, PhD
Professor of Pediatrics, Harvard Medical School;
Samuel E. Lux IV Chair in Hematology Oncology;
Director, Bone Marrow Failure and MDS Program, Dana Farber/Boston Children’s Cancer and Blood Disorders CenterDr. Shimamura directs the Bone Marrow Failure and Myelodysplastic Syndrome Program at Dana Farber/Boston Children’s Cancer and Blood Disorders Center. Her research focuses on translational studies, spanning clinical through basic science investigations to understand the genetic and molecular basis of bone marrow failure, MDS, and leukemia predisposition with the goal of developing more effective and less toxic treatments.
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Lab Members
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Chad Harris, BS, MS
LAB MANAGER
Chad received his BS then MS in Biology/Genetics and Molecular Biology respectively from Ball State University. He then started working in the Lab of David A. Williams MD, where he continues to manage. He is currently the chair of the Laboratory Safety Group (LSG) of the hospital, and is a member of the Institutional Biosafety Committee as well as the Gene and cell therapy scientific review committee. He is coming to the Shimamura lab to fill a management/technical training role.
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Yu Zhou, PhD
POST-DOCTORAL FELLOW
Yu got his PhD in Cellular and Molecular Biology from Tulane University. He focused on transcriptomic and epigenetic analyses using bioinformatic tools during his PhD period. He joined the Shimamura Lab in December 2019. Yu loves road trips on vacation.
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Felicia Andresen, MD
POST-DOCTORA FELLOW
Felicia received her MD at the Technical University of Munich. She completed her pediatric residency in the Department of Pediatrics at the University Hospital Wuerzburg and in the Division of Pediatric Hematology and Oncology at the University Medical Center Freiburg. Felicia is interested in bone marrow failure, pediatric MDS, leukemia predisposition and clonal hematopoiesis with a focus on improving patient management and treatment. goes here
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Helen Reed, MD, MPH
Clinical Fellow
Helen received her MD from the University of Pennsylvania and completed internal medicine-pediatrics residency at Baylor College of Medicine followed by pediatric hematology/oncology fellowship at Dana-Farber/Boston Children's Hospital. She joined Dr. Shimamura's clinical research team in 2022. Her work is focused on clinical outcomes and malignancy risk in inherited bone marrow failure syndromes as well as clinical trial development for this patient population.
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Ashley Gutierrez, BA
Research Technician
Ashley is a graduate of Columbia University where she obtained a BA in Biochemistry. Her primary focus has been purifying and characterizing the functionality of eukaryotic initiation factor 6 (EIF6). Understanding this process is crucial for developing potential therapeutic interventions for SDS patients, as targeting EIF6 may mitigate the risk of leukemia and enhance hematopoietic function. In Fall 2024, Ashley will be pursuing her PhD in Biochemistry and Molecular Biophysics at the University of Chicago.
Clinical Research Team
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Maggie Malsch, RN, BSN
CLINICAL RESEARCH MANAGER
Maggie is the Clinical Research Manager for the Bone Marrow Failure program at Boston Children’s Hospital. Her initial work with Dr. Shimamura was in the lab, where she worked on SDS. Maggie then went back to school to get her nursing degree from Simmons College and her Masters in Clinical Trials from Drexel University. She worked as a bone marrow transplant nurse at Boston Children’s and eventually moved into the role of research nurse and project manager. When Dr. Shimamura returned to Boston Children’s, Maggie jumped at the chance to work with her again.
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Greta Joos, BS
CLINICAL RESEARCH ASSISTANT
Greta is a Clinical Research Assistant at Boston Children's. She joined the team in May 2021 after graduating from Duke University with a Bachelor of Science degree in Biology. She works on the SDS Registry as well as on a variety of other bone marrow failure projects. Greta enjoys connecting with patients and families. Please contact Greta with any questions about the SDSR including how to enroll, request sample collection kits, and/or share medical records.
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Leah Cheng
CLINICAL RESEARCH MANAGER
Leah is a Clinical Research Manager with the Experimental Therapeutics and Interventional Trials group at Boston Children’s Hospital. Starting in 2017, she began working with Dr. Shimamura coordinating the SDS Registry and since then has also become involved in other bone marrow failure registries and interventional trials as well. Leah very much enjoys working with both the SDS Registry patients and the research team.
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Ian Atkinson
CLINICAL RESEARCH ASSISTANT
Ian is a graduate of Cornell University where he obtained a BA in Biology and Society. As a clinical research assistant, he works collaboratively with medical providers and research staff on two international registries investigating bone marrow failure. He is passionate about promoting health equity, pediatric research, improving patient treatment/outcomes, and advocating for mental health initiatives.
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Katherine Coyne
INTERN
Katherine is a current candidate for a Bachelor’s of Science in Biochemistry at Northeastern University. She is working in the Shimamura Lab as a student for her co-op starting in January 2022. In the past, she has worked in cancer immunology research and on an inpatient oncology floor as a medical assistant. In her spare time, she loves to run, read, try new foods, and spend time with family and friends.
Administrative Associate
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Porscha Wells
Porscha graduated from Umass Boston with a BA in psychology. Now, she is looking to pursue a career in health care administration. When she's not working she enjoys reading, hanging out with friends and traveling.
Lab Alumni
John Svenson, PhD
Faculty Associate, School of Mathematical and Natural Sciences, Arizona State University
Rebecca Leary, PhD
Lab Head in Next Generation Diagnostics at Novartis Institutes for Biomedical Research, Cambridge, MA
Karyn Austin, MD PhD
Pediatric Cardiology Fellow, Boston Children’s Hospital
Karthik Ganapathi, MD PhD
Associate Professor, Laboratory Medicine
UCSF
Trisha Wong, MD
Associate Professor of Pediatrics, Hematology/Oncology
Oregon Health Science University
Tomoka Nakamura, MSPH
World Health Organization (WHO)
Michael Zhang, MD PhD
Residency in Radiation Oncology, UCSF
Sioban Keel, MD
Assistant Professor in Hematology, University of
Washington
Nicholas Burwick, MD
Assistant Professor of Hematology, University of Washington
Phoenix Ho, MD
Associate Medical Director, Clinical Development
Seattle Genetics
Angela Scott, MD
Pediatrics, Seattle, WA
Aaron Seo, MD PhD
Residency in Radiation Oncology, University of Texas, Austin
Takehito Furuyama, PhD
Writer/Author
Melisa Ruiz-Gutierrez, MD PhD
Assistant Professor of Pediatrics, Boston University School of Medicine
Elissa Furutani, MD
Medical Director, Keros Therapeutics
Jonas Guderas
Chris Reyes
Ashley Galvin
Gwen Muscato
Kiki Ballotti